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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC2
All Species:
16.36
Human Site:
T497
Identified Species:
45
UniProt:
Q53ET0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53ET0
NP_859066.1
693
73302
T497
S
P
S
L
V
L
P
T
Q
P
H
T
P
K
S
Chimpanzee
Pan troglodytes
Q5IS70
1186
124883
K791
E
G
S
K
L
A
K
K
R
A
D
L
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001112030
694
73257
T498
S
P
S
L
V
L
P
T
Q
P
H
T
P
K
S
Dog
Lupus familis
XP_855142
696
72986
S500
P
P
S
L
V
L
P
S
Q
A
P
T
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U182
692
73197
T498
P
P
S
L
V
I
P
T
H
P
P
T
P
K
S
Rat
Rattus norvegicus
Q3LRZ1
691
73127
S497
P
P
S
L
V
I
P
S
H
P
P
T
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
S444
A
G
S
P
A
N
Q
S
P
T
S
P
V
S
N
Frog
Xenopus laevis
Q52KS4
632
69330
V456
N
F
Q
P
P
S
P
V
P
C
P
P
L
D
L
Zebra Danio
Brachydanio rerio
XP_698544
527
57276
P351
L
S
S
S
L
S
N
P
S
I
Q
A
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.8
98.4
89.6
N.A.
92.2
92
N.A.
N.A.
38.9
37.2
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
31.1
98.5
92.9
N.A.
94.2
94.3
N.A.
N.A.
52.3
50.7
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
66.6
N.A.
73.3
66.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
73.3
N.A.
80
80
N.A.
N.A.
26.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
12
0
0
0
23
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
23
0
23
0
0
0
0
% H
% Ile:
0
0
0
0
0
23
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
12
12
0
0
0
0
0
56
12
% K
% Leu:
12
0
0
56
23
34
0
0
0
0
0
12
12
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% N
% Pro:
34
56
0
23
12
0
67
12
23
45
45
23
56
0
12
% P
% Gln:
0
0
12
0
0
0
12
0
34
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
23
12
89
12
0
23
0
34
12
0
12
0
12
12
45
% S
% Thr:
0
0
0
0
0
0
0
34
0
12
0
56
0
0
12
% T
% Val:
0
0
0
0
56
0
0
12
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _